Pulmonary Arterial Hypertension (PAH) causes the right ventricle to be strained, increasing the risk of heart failure in those who are affected. Its clinical appearance resembles that of many other diseases, delaying identification until the condition has progressed further. It is still one of the most common causes of death in individuals with Sickle Cell Anemia (SCA) all over the world. Even with a moderate rise of pulmonary artery pressure, it confers a considerable risk of death, with two-year mortality rates as high as 40%-50%. The median age of survival after being diagnosed with the condition is 25.6 months. Early detection of high pulmonary artery pressure in children and appropriate action, such as anti-hemolytic drug optimization, may help to avoid this problem from progressing
